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Purpose: The purpose of this study is to understand the actual status of fundamentals of nursing practice (FNP) education at nursing colleges, and the difficulties of FNP operation in the early stages of the COVID-19. Methods: This study used a descriptive design. Data collection was conducted from December 9, 2020 to January 31, 2021 using the self-report questionnaire method for a total of 95 nursing colleges. The questionnaire consisted of characteristics related to FNP, changes in FNP education, difficulties in operating FNP, and countermeasures in the COVID-19 situation. Results: Changes in FNP due to COVID-19 were distribution of practice places, reduction of the number of students, short-term intensive classes, and reduction of face-to-face practice. Most colleges conducted FNP face-to-face, but some schools showed that FNP was conducted non-face-to-face. The difficulties of operating FNP that instructors experienced induced concerns about a decrease in student competency due to lack of face-to-face practice and an unofficial increase in the number of teaching hours and physical demands on instructors due to the expansion of the division. Conclusion: In order to develop the capabilities of nursing students in other pandemic situations in the future, it is necessary to find systematic coping strategy to reduce the burden of FNP instructors, and to develop non-face-to-face online practice contents and consumables for online practice. © 2022 Korean Academy of Fundamentals of Nursing.
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An 18-year-old female with neurofibromatosis presented for enucleation biopsy of a slow-growing soft tissue mass on her right anteromedial arm during the COVID-19 pandemic. Ultrasonography was used in the mapping of the brachial plexus and the identification of possible neurofibroma along peripheral nerves. An interscalene brachial plexus nerve block was successfully and safely achieved with ultrasonographic and peripheral nerve stimulator guidance. Ultrasound-guided and nerve stimulator-guided peripheral nerve blocks are safe and viable anesthetic management options for patients with neurofibromatosis, especially in this time of the COVID-19 global pandemic. © 2022 University of the Philippines Manila. All rights reserved.
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Community service has become an indispensable source of service in people's life, but the traditional way of service can't meet people's fast pace of life. Therefore, smart community (smart city) appears in people's vision, which can greatly improve the quality of our life and reduce the inconvenient factors that life may bring. The smart community designed and studied in this paper is divided into five functional modules: user login and registration function, function selection, personnel management, vehicle management, health management module. Among them, the login function, function selection, personnel management module is to interact with the database, to achieve the transmission of information. The health management module is based on the naive Bayes algorithm to classify the safety level of COVID-19, a currently popular influenza virus, to realize the health monitoring of community personnel and prevent the continuous spread of Novel Coronavirus. The intelligent community can ensure the integrity of data and information, simple operation, perfect function and superior performance. At the same time, the intelligent community combined with the naive Bayes algorithm for health management design, embodies the development principle of intelligent community, people-oriented. © 2022 IEEE.
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This study aims to present the problems and solutions of live shopping to suggest the direction of live commerce broadcasting in the future by examining the influence of the types of impulse buying on consumers’ emotional responses and the reuse intention according to changes into non-contact economy due to the COVID-19 pandemic. To achieve the purpose of this study, the theoretical foundation of related factors was established based on literature research and previous studies. Accordingly, research models and research hypotheses were presented. To verify the hypothesis, a survey was conducted through an online survey method targeting 300 consumers who have experience using live shopping in China. The statistical analysis was conducted by frequency analysis, exploratory factor analysis, correlation analysis and multiple regression analysis using SPSS26.0 program. The results of the empirical analysis and implications of this study are as follows. First, pure impulse buying, planned impulse buying, stimulus impulse buying and reminder impulse buying had a significant positive (+) effect on jealousy and vanity of emotional response. Therefore, the seller of the product is expected to increase sales by stimulating customers ’ impulse buying. In addition, the purchaser may meet emotional responses such as jealousy or vanity, but this may lead to economic losses or unnecessary product purchases. Second, jealousy and vanity of emotional response had a significant positive (+) effect on reuse intention. Therefore, the purchaser should try to find ways to reduce emotional responses such as jealousy and vanity. Third, pure impulse buying, planned impulse buying, stimulus impulse buying and reminder impulse buying had a significant positive (+) effect on reuse intention. Therefore, impulse buying can lead to product purchase even if there is no stimulus of emotional reaction such as jealousy or vanity, so product buyers should exclude the factors that can cause impulse buying as much as possible. This study also aims to present the research results and implications based on some limitations in the process of the study. First, if the study is conducted for all age groups, it is expected that the results of more objective research will be derived. Second, if comparative research is conducted on live shopping users in various countries, it is judged that strategies will be derived to help identify the tendency of live shopping users by country and to establish marketing strategies for product sellers. © 2022, Success Culture Press. All rights reserved.
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In Hispanic populations, rates of metabolic comorbidities such as obesity are higher than that of non-Hispanic White in the United States. Despite having higher comorbidity rates, Hispanic populations have a lower total risk of mortality compared to non-Hispanic counterparts. In this study, we explore whether this paradox exists for COVID-19 related deaths in Hispanic patients with Metabolic Syndrome (MetS). MetS is defined by the WHO as having at least 3 of the following 5 criteria: obesity, hypertension, diabetes, hypertriglyceridemia, and low levels of HDL. A retrospective study was conducted of patients hospitalized for COVID-19 between January 1, 2020 and May 1, 2021 at a regional county hospital in Southern California. In this cohort of 269 patients, 55.4% were male, mean age was 58.4 (IQR, 48-68) years, 63.9% had obesity, 42.4% had hypertension, 40.1% had diabetes, 18.2% had hypertriglyceridemia, and 32.3% had low HDL levels, and 30.9% fit the criteria for MetS. The racial demographic of this cohort was 78.8% Hispanic, 6.32% African American, 4.46% White and 3.72% Asian. Odds ratios and confidence intervals for the relationship between MetS and mortality were calculated separately among patients who were either Hispanic or non-Hispanic. Multivariable logistic regressions accounting for interactions between MetS and Hispanic patients were assessed. In our cohort, 49 (18.2%) patients died of COVID-19. Hispanic patients had a lower probability of mortality (16.0%;95% CI 11.1-21.0) than non-Hispanic patients (26.3%;95% Cl 14.9-37.7). Hispanic patients with MetS had a higher risk of mortality from COVID-19 ([OR] 1.57;95% Cl 0.74-3.33) compared to Hispanic patients without MetS. Non-Hispanic patients with MetS also had a higher risk of mortality from COVID-19 ([OR] 4.38;95% Cl 1.19-16.03) compared to non-Hispanic patients without MetS. The MetS effect on mortality in Hispanic was 64% lower than that in non-Hispanic patients, although this result did not reach statistical significance (p value=0.18.) Our data suggests that MetS is a risk factor for COVID-19 mortality and MetS may have a lower impact on COVID-19 related death in the Hispanic population than non-Hispanic counterparts. Studies with larger sample sizes will be required to confirm these relationships.Presentation: Sunday, June 12, 2022 12:30 p.m. - 2:30 p.m.
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This study aimed to explore the possibility of using Mauremys mutica oligopeptides as raw materials to develop a drug targeting the SARS-CoV-2 virus. M. mutica oligopeptides were prepared through the combined enzymatic hydrolysis of M. mutica meat using flavoenzyme and papain, and the optimal enzyme ratios, enzyme dosage, pH, and enzymatic hydrolysis time were determined using single-factor and orthogonal experiments. After separating the oligopeptide fractions via high-performance liquid chromatography-mass spectrometry (HPLC-MS), Peak Studio and Peptide Ranker were used for peptide sequence analysis and peptide activity prediction, respectively, to screen for oligopeptides with high bioactivity. Finally, the binding ability of oligopeptides with high predicted activity against the SARS-CoV-2 spike protein receptor-binding domain (RBD) was evaluated using molecular docking. The results show that the highest degree of hydrolysis (DH;42.56%) was obtained when M. mutica meat was treated with a flavoenzyme: papain ratio of 7:3 and an enzyme dosage of 7% at pH 5.5 for 4 h. According to Peak Studio analysis, 510 peptides with an average local confidence (ALC) of > 90% were discovered. Six oligopeptides with high Peptide Ranker scores (LDFFK, LDFFKAL, FRVL, AFRVL, AGGKPFQ, and SPFRVT) were screened to dock with S protein. Their docking scores ranged from -138.50 to -169.68, and the lowest docking score (-169.68) was exhibited by LDFFKAL. Therefore, a high DH of M. mutica meat could be attained after process optimization, and a high inhibitory potential for SARS-CoV-2 was observed in the resulting M. mutica oligopeptides. © 2022 South China University of Technology. All rights reserved.
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Objective: Since the onset of the COVID-19 pandemic, it has been reported that those who are overweight, have diabetes mellitus (DM), or underlying vascular diseases were more likely to get severely ill from COVID-19. The goal of our study is to examine the association of these effects with COVID-19 severity in patients with metabolic syndrome (MetS), which is defined by the WHO as having at least 3 of the following 5 criteria: obesity, hypertension, DM, hypertriglyceridemia, and low levels of HDL. Methods: A retrospective study was conducted of patients hospitalized for COVID-19 between January 1, 2020 and May 1, 2021 at a regional county hospital in Southern California. In this cohort of 269 patients hospitalized for COVID-19, 44.6% were Female, mean age was 58.4 (IQR, 48-68) years, 63.9% had obesity, 42.4% had hypertension, 40.1% had diabetes, 18.2% had hypertriglyceridemia, and 32.3% had low HDL levels, and 30.9% fit the criteria for MetS. The racial demographic of this population was 78.8% Hispanic, 6.32% African American, 4.46% White and 3.72% Asian. 40 (14.9%) were intubated, 51 (18.9%) required admittance to the intensive care unit (ICU), 140 (52.0%) had acute respiratory failure (ARF), and 49 (18.2%) patients died. Unadjusted significance was assessed with chi-squared statistics. Multivariate logistic regression was used to adjust for race, age, and sex, and to examine the relationship between MetS and the outcome variables: intubation, ICU admittance, ARF, and mortality. Results: Unadjusted analysis of this cohort showed that MetS patients, when compared with non-MetS patients, had a higher risk of mortality (25.3% vs. 15.1%;p-value < 0.05), admittance rate to the ICU (27.7% vs. 15.1%;p-value < 0.05), intubation rates (18.1% vs. 13.4%;p-value = 0.3), but a lower incidence of ARF (47.0% vs. 54.3%;p-value =0.3). In multivariate analysis with covariates of age, sex and race, MetS patients were statistically significantly associated with mortality ([OR] 2.38;95% CI, 1.13-5.01;p-value < 0.05) and requiring ICU care ([OR] 1.99, 95% CI, 1.03-3.84;p-value < 0.05). However, MetS was not significantly associated with intubation ([OR] 1.27;95% CI, 0.60-2.68;p-value = 0.53) or with ARF ([OR] 0.69;95% CI, 0.40- 1.19;p-value = 0.18). Discussion/Conclusion: Our data suggests that MetS is strongly associated with worse COVID-19 outcomes, in a predominantly hispanic population. Further analysis of individual components of metabolic syndrome may yield a more detailed understanding of the drivers of COVID-19 outcomes. This work contributes to an understanding of the effects of MetS on COVID-19 outcomes in a broader population and community setting.
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This special issue contains articles that discuss the relation and interplay of immunopsychiatry and the ongoing COVID-19 pandemic.